APA
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Sakurai, H., Nagaswami, M., Tan, E., Meyer, A. K., Streeter, C., Jain, F., … Nyer, M. (2021). A Patient with Treatment-resistant Depression Who Achieved Remission with Heated Yoga: A Case Report. Clinical Neuropsychopharmacology and Therapeutics.
Chicago/Turabian
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Sakurai, H., Megha Nagaswami, Emily Tan, Ashley K Meyer, C. Streeter, F. Jain, Simmie L. Foster, et al. “A Patient with Treatment-Resistant Depression Who Achieved Remission with Heated Yoga: A Case Report.” Clinical Neuropsychopharmacology and Therapeutics (2021).
MLA
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Sakurai, H., et al. “A Patient with Treatment-Resistant Depression Who Achieved Remission with Heated Yoga: A Case Report.” Clinical Neuropsychopharmacology and Therapeutics, 2021.
BibTeX Click to copy
@article{h2021a,
title = {A Patient with Treatment-resistant Depression Who Achieved Remission with Heated Yoga: A Case Report},
year = {2021},
journal = {Clinical Neuropsychopharmacology and Therapeutics},
author = {Sakurai, H. and Nagaswami, Megha and Tan, Emily and Meyer, Ashley K and Streeter, C. and Jain, F. and Foster, Simmie L. and Yeung, A. and Cusin, C. and Fava, M. and Mischoulon, D. and Nyer, M.}
}
Novel interventions are needed to manage treatment-resistant depression (TRD), defined as patients who do not respond to two or more antidepressant trials of adequate dose and duration. We report on a 28-year-old female with TRD with nonresponse to several adequate trials of antidepressants who experienced full symptomatic remission after participating in the heated hatha yoga (HY) arm of a randomized controlled trial (RCT) for depression. Patients, including the one of interest, were randomized to 8 weeks of at least twice weekly HY or an 8-week waitlist followed by 8 weeks of HY. HY incorporates yoga plus heat through a series of standardized poses performed in a heated room (105° F). The 30-item Inventory of Depressive Symptoms, Clinician-Rated (IDS-C30) and 28-item Hamilton Depression Rating Scale (HAM-D28) were assessed at key time points throughout the study. The patient attended 16 classes over 8 weeks. Her baseline IDS-C30 score of 42 decreased to 26 following 2 weeks of HY, and continued declining throughout the intervention, with a final score of 6 (remission) after 8 weeks. HAM-D28 scores decreased from 26 at baseline to 4 (remission) after 8 weeks. At the 1-month follow-up, the patient’s scores remained stable at 4 on IDS-C30 and 7 on HAM-D28, respectively. HY may serve as a potential intervention for TRD in patients who have not previously responded to conventional antidepressants. The rigorousness of the intervention must be considered regarding recommendations for use in the general population.